Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Sep;142(3):275–288. doi: 10.1085/jgp.201310975

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2013 Perry et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 6. — Perturbations to inactivation gating and activation gating show poor correlation for S4 residue mutations. Plot comparing perturbations to ΔG⁰, versus WT, of inactivation gating (ΔΔG⁰_Inact, represented by Δlog(K_eq,0)) compared with perturbations to ΔG⁰, versus WT, of activation gating (ΔΔG⁰_Activ; see Materials and methods) for each S4 residue mutation. Solid black line represents linear regression analysis constrained to go through WT, whereas dashed gray line is an unconstrained fit (R² = 0.38).