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. 2013 Jun 14;41(15):7522–7535. doi: 10.1093/nar/gkt513

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© The Author(s) 2013. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — The 2° structures and domain architectures of the 23S and 5S rRNAs of E. coli. (a) The traditional 2° structure^phylo, which is sheared into two fragments, and contains a central single-stranded region and six domains (Domain I, purple; Domain II, blue; Domain III, magenta; Domain IV, yellow; Domain V, pink; Domain VI, green), and (b) 2° structure^3D, which accurately represents all helices, and contains seven domains (Domain 0 in orange; Domains I-VI are colored as in panel 1a). In 2° structure^phylo, the central single-stranded region is partitioned between multiple domains, whereas in 2° structure^3D, that same rRNA is double-helical and is fully contained within Domain 0. The 5S rRNA is light green and is placed in the proximity of Domain II in 2° structure^3D to reflect its position in three dimensions and its interactions with the 23S rRNA.