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Domain 0, the central core of the 23S rRNA, to which all other 23S rRNA domains are rooted. (a) 2° Structure of Domain 0. The helices are numbered and distinguished by color. The coloring of helices is consistent with Figure 2. Helix 26a, with an extruded G and non-canonical base pairs, is orange. (b) The 3D structure of Domain 0, taken from the X-ray structure of the LSU, with the same helical coloring scheme as in (a). (c) Domain 0 rotated by 180° relative to (b).
