. Author manuscript; available in PMC: 2013 Aug 27.

Published in final edited form as: Sci Transl Med. 2012 Sep 26;4(153):153ra131. doi: 10.1126/scitranslmed.3004186

Table 1.

Demographic characteristics of subjects used in the study. Values are reported as means (SD). T₂LV: T₂ hyperintense lesion volume.

	GA (n = 94)	IFN-β (n = 128)	Untreated (n = 141)	Adjusted P value^*
Female, n (%)	68 (73)	95 (74)	117 (85)	0.0344
Disease subtype (CIS/RR)	7/87	9/119	32/109	0.0001
Symptom duration at sampling	6.12 (6.36)	6.65 (6.36)	7.48 (8.06)	0.5644
Age at first symptom	34.23 (9.19)	34.77 (9.30)	33.35 (9.07)	0.4841
BPF	0.885 (0.034)	0.871 (0.036)	0.880 (0.040)	0.0178
EDSS	1.04 (1.01)	1.19 (1.04)	1.07 (1.09)	0.5539
T₂LV^**	3.19 (2.58)	3.65 (2.64)	3.93 (4.75)	0.1720

Adjusted for symptom duration, age at first symptom, and gender (unless outcome of interest). MRI measurements were captured in a time window of 6 months before or after sampling.

^**

P value from model with natural log transformation of T₂ lesion volume value.