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. 2013 Sep;5(9):a012658. doi: 10.1101/cshperspect.a012658

Figure 1.

Figure 1.

Access/prime/repair/restore model for the role of chromatin in the DDR. Chromatin remodeling and histone modification enzymes regulate both the accessibility of the lesion to repair factors as well as providing a platform for signaling repair events to other cellular processes. See text for details.