Table 7.
Characteristics of subjects who developed articular RA during follow-up.
| Subject 1 | Subject 2 | Subject 3 | |
|---|---|---|---|
| Age in years | 70 | 36 | 67 |
| Gender | Male | Male | Female |
| Smoking history | 13 pack years | None | None |
| Current smoker | No | No | No |
| Anti-CCP titer | 175 IU | 136 IU | 92 IU |
| RF titer | 366 IU | Negative | 718 IU |
| HRCT pattern | Isolated airways disease | Isolated airways disease | Airways disease & ILD |
| Histopathology (TBBx) | None | Lymphoplasmacytic inflammation | Lymphoplasmacytic and eosinophilic inflammation |
| Time to development of articular RA | 234 days | 561 days | 261 days |
RF=rheumatoid factor, RA=rheumatoid arthritis, CCP=cyclic-citrullinated peptide, IU=international units, ILD=interstitial lung disease, HRCT=high resolution computed tomography, and TBBx=transbronchial biopsy.