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. Author manuscript; available in PMC: 2013 Aug 27.
Published in final edited form as: JACC Cardiovasc Imaging. 2012 May;5(5):540–549. doi: 10.1016/j.jcmg.2011.12.019

Table 3.

Intravascular ultrasound measurements in patients already receiving clopidogrel at enrolment by groups according to platelet reactivity status (HPR versus no HPR).

Overall group HPR No HPR P-value

n=203 n=58 n=145
Reference site*
  EEM CSA, mm2 11.6 [9.3, 15.0] 11.9 [10.2, 14.5] 11.4 [9.1, 15.4] 0.461
  Lumen CSA, mm2 6.3 [5.0, 7.6] 6.4 [5.3, 7.6] 6.3 [5.0, 7.6] 0.659
  Plaque burden 0.46 [0.38, 0.53] 0.47 [0.39, 0.53] 0.46 [0.38, 0.52] 0.592
Minimum Lumen area site
  EEM CSA, mm2 10.7 [8.7, 13.9] 10.6 [8.5, 13.9] 10.7 [8.8, 13.9] 0.829
  Lumen CSA, mm2 3.0 [2.3, 3.7] 3.0 [2.5, 3.8] 3.0 [2.2, 3.7] 0.485
  Plaque&media CSA, mm2 7.5 [5.5, 10.3] 7.7 [5.5, 9.9] 7.5 [5.5, 10.3] 0.714
  Plaque burden 0.71 [0.64, 0.77] 0.72 [0.63, 0.77] 0.71 [0.65, 0.78] 0.867
Volumetric Data
  EEM volume, mm3 92.3 [55.8, 174.4] 106.4 [67.8, 200.3] 86.8 [51.8, 161.2] 0.0962
  Lumen volume, mm3 37.4 [22.6, 59.5] 42.2 [26.3, 69.5] 34.7 [20.5, 53.8] 0.0526
  Plaque&media volume, mm3 56.0 [32.9, 110.6] 67.4 [37.4, 127.5] 51.3 [30.9, 102.9] 0.111
  Plaque burden 0.62 [0.55, 0.66] 0.61 [0.56, 0.67] 0.62 [0.55, 0.66] 0.822
  Lesion length, mm 7.6 [5.3, 13.0] 8.6 [6.4, 14.5] 7.3 [4.9, 12.5] 0.0652
  Calcium length, mm 4.4 [1.3, 8.7] 7.0 [2.9, 11.0] 3.8 [1.1, 6.9] 0.0022
  Maximum calcium arc, ° 100 [40, 180] 125 [70, 270] 90 [33, 165] 0.0055
  Calcium index 0.15 [0.03, 0.42] 0.28 [0.07, 0.53] 0.11 [0.02, 0.40] 0.0116
  Remodeling index 0.91 [0.79, 1.03] 0.90 [0.78, 1.04] 0.91 [0.80, 1.02] 0.954
*

Calculated as the average of proximal and distal reference sites. EEM = external elastic membrane, CSA = cross sectional area