Figure 11.

Effects of Lu AF21934 on the MK-801-induced deficits in social interaction test. The graphs represent the disruption in the number of social episodes (A) and in the total duration of social episodes (B). Lu AF21934 was given 60 min before the test, and MK-801 was administered 3.5 h before the test. Values in parentheses represent the doses of the compounds in mg·kg⁻¹. Data are presented as mean ± SEM. ^#P < 0.01 versus control group, *P < 0.05 and **P < 0.01 versus MK-801-treated group; one-way anova analysis followed by Tukey's post hoc tests. The control experiments without MK-801 administration are represented by the panels C and D. The control experiments without MK-801 administration are represented by the panels C and D.