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Localization and phenotypes of the rpo21-4 and rpb1-84 mutations. (A) Schematic view of the conserved region of the foot (dark blue ribbon) and the foot domain (light blue) of S. cerevisiae RNA pol II in the structure of the complex and the positions of foot mutations (red ribbons and arrows). (B) Growth of wild-type (WT) S. cerevisiae and of the rpo21-4 and rpb1-84 mutants.
