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. 2013 Sep;61(9):639–648. doi: 10.1369/0022155413492771

Figure 2.

Figure 2.

Different GP73 immuno-staining patterns in hepatocellular carcinoma (HCC) cells and non-HCC cells. (A) The immunostaining pattern of GP73 in HCC cells showed a diffuse coarse-block pattern. In contrast, the surrounding non-HCC cells showed a diffuse fine-granular pattern. (B) The coarse blocks were perinuclear. (C) The coarse blocks were concentrated in a certain part of the cytoplasm that gave a cluster- or cord-like appearance. (D) The coarse blocks were concentrated near the lumen of glandular structures. (E) The surrounding non-HCC cells showed a diffuse fine-granular pattern in the cytoplasm. (F) A case of a high-grade dysplastic nodule, which showed a diffuse fine-granular pattern with no difference in intensity between dysplastic cells and surrounding liver cells. Bars = 100 µm.