Fig 2.

RSV A2–2-20F infection results in early lung lesions in BALB/cJ mice. BALB/cJ mice were mock infected or infected with 10⁵ PFU of the indicated strain. Lungs were harvested on day 1 postinfection, stained with H&E, and analyzed for histologic changes. (A) Interstitial pneumonia (IP) score for each group. *, significant difference from mock-infected animals (P < 0.01, ANOVA); **, significant difference from mock- and A2-infected animals (P < 0.05, ANOVA). (B) Representative airways indicating interstitial pneumonia in mock-, A2-, 2-20-, and A2–2-20F-infected mice. (C) Representative airways containing cell debris in mock-, A2-, 2-20-, and A2–2-20F-infected mice. The results shown represent those from two experiments with similar data.