Fig 8.

In vivo antiviral efficacies of peptides (higher viral dose). A CAU peptide dose of 1.6 mg/kg was administered to chickens 2 days or 1 day before infection (i.e., Day −2, Day −1), concurrently with infection (i.e., Day 0), and 1 or 2 days after infection (i.e., Day 1, Day 2). Meanwhile, the chickens were challenged by intranasal point eye inoculation with 100 μl of a solution containing 200 PFU of NDV. (A) Injections were repeated on day 6 p.i. (total of five animals per group). (B) Injections were repeated three times at 3-day intervals (total of five animals per group).