Table 2.
Strain and day postinfection | Viremia (no. of positive mice/total no. of mice) |
---|---|
T3DF | |
1 | 1/5 |
2 | 0/5 |
4 | 0/5 |
rsT3DF/T3DCS1 | |
1 | 7/8 |
2 | 6/8 |
4 | 4/8 |
rsT3DF/T3DCS1 σ1s-null | |
1 | 3/5 |
2 | 3/5 |
4 | 1/5 |
CBA/J mice were inoculated intranasally with 107 PFU T3DF, rsT3DF/T3DCS1, or rsT3DF/T3DCS1 σ1s-null. Blood was collected by heart puncture at the indicated times postinoculation, and viral titers were determined by plaque assay using L929 cells. Results are expressed as the number of mice with detectable virus in the blood (limit of detection, 10 PFU/ml).