Table 2.
M79-dependent expression of MCMV ORFs
| ORF | Stranda | Downregulation by:b |
Kineticsc | |
|---|---|---|---|---|
| PAA treatment | M79 mutation | |||
| m011 | Y | Y | L | |
| m012 | Y | Y | L | |
| m014 | Y | Y | L | |
| M032 | C | Y | Y | L |
| M035 | Y | Y | L | |
| m039 | C | Y | Y | L |
| m040 | C | Y | Y | ND |
| M046 | C | Y | Y | |
| M053 | Y | Y | L | |
| M055 | C | Y | Y | L |
| M056 | C | Y | Y | L |
| M072 | C | Y | Y | L |
| M073 | Y | Y | L | |
| M074 | C | Y | Y | L |
| M075 | C | Y | Y | L |
| M076 | Y | Y | ND | |
| M077 | Y | Y | L | |
| M080 | Y | Y | L | |
| M084 | C | Y | Y | ND |
| M085 | C | Y | Y | L |
| M086 | C | Y | Y | L |
| M096 | Y | Y | L | |
| M100 | C | Y | Y | L |
| M104 | C | Y | Y | L |
| M114 | C | Y | Y | L |
| M115 | C | Y | Y | L |
| M116 | C | Y | Y | L |
| M118 | C | Y | Y | L |
| m119.1 | C | Y | Y | L |
| m131 | C | Y | Y | L |
| m155 | C | Y | Y | L |
| m156 | C | Y | Y | L |
| m157 | C | Y | Y | ND |
| m158 | C | Y | Y | ND |
| m159 | C | Y | Y | L |
| m160 | C | Y | Y | L |
| m161 | C | Y | Y | L |
| m162 | C | Y | Y | L |
| m163 | C | Y | Y | |
| m165 | C | Y | Y | |
| m168 | Y | Y | L | |
| m164 | C | N | Y | |
| m166 | C | N | Y | |
| m001 | C | Y | N | ND |
| m002 | Y | N | ND | |
| m003 | Y | N | ||
| m007 | Y | N | L | |
| m015 | Y | N | L | |
| m016 | Y | N | L | |
| m018 | C | Y | N | |
| m019 | Y | N | ND | |
| m021 | Y | N | ND | |
| m022 | Y | N | ND | |
| M023 | C | Y | N | |
| m023.1 | Y | N | ND | |
| M024 | C | Y | N | ND |
| M025 | Y | N | L | |
| m025.1 | C | Y | N | L |
| m025.2 | C | Y | N | L |
| m025.3 | C | Y | N | ND |
| m025.4 | C | Y | N | ND |
| M026 | C | Y | N | |
| M027 | C | Y | N | |
| m029 | Y | N | ||
| m030 | Y | N | ||
| M031 | Y | N | ||
| M031b | Y | N | ND | |
| M033 | Y | N | ND | |
| M044.1 | Y | N | ND | |
| M044.3 | Y | N | ND | |
| m045.2 | C | Y | N | ND |
| M050 | C | Y | N | L |
| M052 | Y | N | L | |
| m069.1 | Y | N | ND | |
| M071 | Y | N | L | |
| M073x2d | Y | N | ND | |
| M082 | C | Y | N | L |
| M083 | C | Y | N | L |
| M087 | Y | N | ||
| M088 | Y | N | ||
| M089x1 | C | Y | N | L |
| m090 | C | Y | N | L |
| M091 | Y | N | ||
| M092 | Y | N | ||
| M093 | Y | N | L | |
| M094 | Y | N | L | |
| M095 | Y | N | L | |
| M097 | Y | N | ||
| M098 | Y | N | ||
| M099 | Y | N | L | |
| M103 | C | Y | N | L |
| m106 | C | Y | N | L |
| m106.1 | C | Y | N | ND |
| m106.3 | C | Y | N | ND |
| m107 | Y | N | L | |
| m108 | C | Y | N | L |
| m117 | C | Y | N | ND |
| m117.1 | Y | N | ND | |
| m119.5 | Y | N | L | |
| M121 | C | Y | N | L |
| m123x2 | C | Y | N | ND |
| m124 | Y | N | L | |
| m124.1 | C | Y | N | ND |
| m125 | Y | N | ND | |
| m126 | Y | N | ND | |
| m127 | C | Y | N | ND |
| m128x3 | Y | N | ||
| m129 | C | Y | N | L |
| m130 | Y | N | ND | |
| m134 | Y | N | ND | |
| m136 | C | Y | N | ND |
| m137 | C | Y | N | |
| m144 | C | Y | N | ND |
| m148 | Y | N | L | |
| m149 | Y | N | ND | |
| m167 | C | Y | N | L |
| m170 | C | Y | N | L |
a
C, complementary strand; blank entries, forward strand.
b
The mean intensity of a transcriptional region was (Y) or was not (N) reduced by at least 3-fold in array analysis.
c
Transcription of an ORF is considered to be late kinetics (L) when it is elevated by at least 50% from 12 to 24 hpi, as described by Marcinowski and coworkers (46), or absent at 6.5 hpi but detectable at 24 hpi, as described by Lacaze and coworkers (45). Blank entries, early kinetics. ND, kinetics class has not been previously described.
d
x, exon.