Genetic analysis of KoRV-A and KoRV-J. (A) Comparison of amino acid sequences of KoRV subgroups A and J. Dots indicate the same amino acids. VRA, VRB, and PRR are shaded in gray. Abbreviations: SP, signal peptide; PHQ, PHQ motif; CETTG, CETTG motif; CXXC, CXXC motif; SU, surface unit; TM, transmembrane; RX(K/R)R, furin cleavage site; CXC6, CXC6 motif. (B) Maximum likelihood tree of the entire amino acid sequences of env genes of KoRV isolates and other gammaretroviruses. Numbers at the nodes indicate the percentage of rapid bootstrap values (1,000 replicates). Amino acid sequences used for the analyses were retrieved from the GenBank database, and the accession numbers are shown in parentheses. Abbreviations: X-MLV, xenotropic MLV; enFeLV, endogenous FeLV.