Table 2.
Infection of transgenic mice overexpressing hamster PrPC with frozen or FFPE 263K scrapie-infected hamster brain
| Sample | Brain samplea | Clinical/totalb | Mean dpi ± SDc |
|---|---|---|---|
| 263KFroz | Frozen homogenate | 7/7 | 52 ± 5 |
| 263KFFPE | FFPE-stab | 6/10 | 99 ± 10 |
| 263KFFPE | FFPE-homogenate | 9/9 | 70 ± 7 |
a
Samples were inoculated into Tg7 mice overexpressing hamster PrPC. For both homogenate samples, 50 μl of a 10−2 dilution of the starting material was inoculated intracranially.
b
That is, the number of mice with clinical scrapie over the total number of inoculated mice.
c
That is, the mean disease incubation time in days postinfection (dpi) ± standard deviation (SD) in days.