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Susceptibility of IgA−/− and IgA+/+ mice to pulmonary F. tularensis LVS infection. Groups of six to eight mice were challenged i.n. with 500 CFU of F. tularensis LVS. Weight loss (A) and survival (B) of infected mice were monitored for 20 days. Values are mean percentages ± standard deviations (SD) (error bars). Values that are statistically significantly different (P < 0.05) are indicated by a bar and asterisk.
