Table 3.
MFGPs showing a statistically significant increase in abundance after S. uberis infectiona
| Accession no.b | Description | RSC |
|---|---|---|
| Q6ECI6 | Integrin beta-2 | 5.85 |
| P05164 | Myeloperoxidase | 5.65 |
| Q3SWX7 | Annexin A3 | 5.49 |
| P02544 | Vimentin | 5.23 |
| P21333 | Filamin A | 5.18 |
| Q92176 | Coronin 1A | 5.07 |
| Q258K2 | Myosin 9 | 4.88 |
| P28783 | Protein S100A9 | 4.84 |
| Q1JPB0 | Leukocyte elastase inhibitor | 4.79 |
| P20000 | Aldehyde dehydrogenase, mitochondrial | 4.33 |
| P20700 | Lamin B | 4.14 |
| Q8SPQ0 | Chitinase-3-like protein 1 | 4.10 |
| P27214 | Annexin A11 | 4.09 |
| O46522 | Cytochrome b245 heavy chain | 4.02 |
| P47843 | Solute carrier family 2, facilitated glucose transport 3 | 3.91 |
| Q29477 | Lactotransferrin | 3.85 |
| Q2UVX4 | Complement C3 | 3.81 |
| P11979 | Pyruvate kinase isozyme M1/M2 | 3.67 |
| O75367 | Core histone macro-H2A.1 | 3.58 |
| B6E141 | Haptoglobin | 3.58 |
| Q8VEK3 | Heterogeneous nuclear ribonucleoprotein U | 3.58 |
| Q9XSJ4 | Alpha-enolase | 3.54 |
| A0A1F3 | l-Lactate dehydrogenase A chain | 3.51 |
| Q32LG3 | Malate dehydrogenase, mitochondrial | 3.43 |
| O46521 | Cytochrome b245 light chain | 3.40 |
| Q58CQ2 | Actin-related protein 2/3 complex subunit 1B | 3.32 |
| P61157 | Actin-related protein 3 | 3.23 |
| Q3SYV4 | Adenylyl cyclase-associated protein 1 | 3.19 |
| P46193 | Annexin A1 | 3.16 |
| P00829 | ATP synthase subunit beta, mitochondrial | 3.13 |
| Q3T0E5 | Adipocyte plasma membrane-associated protein | 3.10 |
| Q5E9B1 | l-Lactate dehydrogenase B chain | 3.05 |
| Q0VCG9 | Pentraxin-related protein PTX3 | 3.05 |
| Q28125 | Intercellular adhesion molecule 3 | 3.00 |
| O95498 | Vascular noninflammatory molecule 2 | 2.95 |
| Q9UM07 | Protein-arginine deiminase type 4 | 2.95 |
| Q32LP0 | Fermitin family homolog 3 | 2.89 |
| P19483 | ATP synthase subunit alpha, mitochondrial | 2.88 |
| P11678 | Eosinophil peroxidase | 2.84 |
| Q3UP87 | Neutrophil elastase | 2.78 |
| Q13349 | Integrin alpha-D | 2.78 |
| P02313 | Nonhistone chromosomal protein HMG-17 | 2.78 |
| P10096 | Glyceraldehyde-3-phosphate dehydrogenase | 2.73 |
| P05044 | Sorcin | 2.72 |
| Q9XT27 | Ceruloplasmin | 2.72 |
| Q63610 | Tropomyosin alpha-3 chain | 2.66 |
| Q99N16 | Leukotriene-B4 omega-hydroxylase 2 | 2.60 |
| P52272 | Heterogeneous nuclear ribonucleoprotein M | 2.52 |
| O00160 | Unconventional myosin If | 2.52 |
| P40673 | High-mobility-group protein B2 | 2.52 |
| Q0VCW4 | l-Serine dehydratase/l-threonine deaminase | 2.45 |
| O77774 | Neutrophil cytosol factor 1 | 2.45 |
| O77775 | Neutrophil cytosol factor 2 | 2.45 |
| A7VJC2 | Heterogeneous nuclear ribonucleoproteins A2/B1 | 2.45 |
| P19134 | Serotransferrin | 2.38 |
| Q14739 | Lamin B receptor | 2.37 |
| Q8IZW8 | Tensin 4 | 2.37 |
| P35246 | Pulmonary surfactant-associated protein D | 2.37 |
| Q5R7W2 | Phosphate carrier protein, mitochondrial | 2.37 |
| O15144 | Actin-related protein 2/3 complex subunit 2 | 2.33 |
| Q8BJS4 | SUN domain-containing protein 2 | 2.29 |
| A7MB62 | Actin-related protein 2 | 2.28 |
| P04157 | Receptor-type tyrosine-protein phosphatase C | 2.21 |
| Q96KK5 | Histone H2A type 1-H | 2.20 |
| P21796 | Voltage-dependent anion-selective channel protein 1 | 2.17 |
| O35737 | Heterogeneous nuclear ribonucleoprotein H | 2.12 |
| Q3SYX9 | Actin-related protein 2/3 complex subunit 5 | 2.12 |
| Q3TRM8 | Hexokinase 3 | 2.12 |
| P32007 | ADP/ATP translocase 3 | 2.10 |
| P29350 | Tyrosine-protein phosphatase non-receptor type 6 | 2.03 |
| Q8VC88 | Grancalcin | 2.03 |
| P12725 | Alpha-1-antiproteinase | 2.02 |
| Q9GL30 | Phospholipase B-like 1 | 2.02 |
| Q68CQ1 | Maestro heat-like repeat-containing protein family member 7 | 2.02 |
| Q13838 | Spliceosome RNA helicase DDX39B | 2.02 |
| P54230 | Cathelicidin 1 | 1.97 |
| P02584 | Profilin 1 | 1.96 |
| O75131 | Copine 3 | 1.92 |
| Q56JZ9 | Glia maturation factor gamma | 1.92 |
| P85521 | Scavenger receptor cysteine-rich type 1 protein M130 | 1.92 |
| Q2KJD0 | Tubulin beta-5 chain | 1.92 |
| P28782 | Protein S100A8 | 1.86 |
| P02253 | Histone H1.2 | 1.82 |
| P30358 | Arachidonate 5-lipoxygenase-activating protein | 1.81 |
| Q5MIB5 | Glycogen phosphorylase, liver form | 1.81 |
| O02849 | Protein-arginine deiminase type 3 | 1.81 |
| D3ZZL9 | GRIP and coiled-coil domain-containing protein 2 | 1.81 |
| Q3T149 | Heat shock protein beta-1 | 1.78 |
| P13796 | Plastin 2 | 1.76 |
| Q3T035 | Actin-related protein 2/3 complex subunit 3 | 1.75 |
| Q95218 | Deleted in malignant brain tumor 1 protein | 1.73 |
| P41976 | Superoxide dismutase [Mn], mitochondrial | 1.72 |
| P48975 | Actin, cytoplasmic 1 | 1.69 |
| Q5E9J1 | Heterogeneous nuclear ribonucleoprotein F | 1.69 |
| A4IF97 | Myosin regulatory light chain 12B | 1.69 |
| P50415 | Cathelicidin 3 | 1.67 |
| P81947 | Tubulin alpha-1B chain | 1.65 |
| Q3ZBV8 | Threonine-tRNA ligase, cytoplasmic | 1.63 |
| Q8BFZ3 | Beta-actin-like protein 2 | 1.60 |
| P62803 | Histone H4 | 1.59 |
| P09769 | Tyrosine-protein kinase Fgr | 1.58 |
| P17453 | Bactericidal permeability-increasing protein | 1.56 |
| P17697 | Clusterin | 1.55 |
| Q148J6 | Actin-related protein 2/3 complex subunit 4 | 1.55 |
| P47791 | Glutathione reductase, mitochondrial | 1.53 |
| A7E3Q8 | Plastin 3 | 1.52 |
a
Significant (P ≤ 0.05, beta-binomial test) increase in abundance (RSC > 1.5) after S. uberis infection (third day after the second inoculation) according to LTQ-Orbitrap GeLC-MS/MS.
b
Accession number in the Uniprot database.