Table 2.
MICs following repeated exposure to naftifine hydrochloride
Isolate | MIC (μg/ml) after the indicated exposure |
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---|---|---|---|---|---|
Initial | Passage 15 |
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0.5× | 1× | 2× MIC | 4× MIC | ||
T. mentagrophytes MRL 10799 | 0.03 | 0.06 | 0.06 | 0.06 | 0.06 |
T. mentagrophytes MRL 10759 | 0.06 | 0.06 | 0.06 | 0.06 | 0.06 |
T. mentagrophytes MRL 10840 | 0.06 | 0.06 | 0.06 | 0.06 | 0.06 |
T. tonsurans MRL 10152 | 0.06 | 0.06 | 0.06 | 0.06 | 0.06 |
T. tonsurans MRL 10260 | 0.12 | 0.06 | 0.06 | 0.06 | 0.06 |
T. tonsurans MRL 10326 | 0.12 | 0.06 | 0.06 | 0.06 | 0.06 |