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Efficacy of antibiotic therapy for S. aureus rat endocarditis in the relapse treatment study. Animals were infected with strains TX0117 and TX0117c; antibiotics were given for 3 days, and animals were sacrificed 3 days after stopping them. Two rats, both in the CFZ-treated, TX0117-infected group, died 24 h after stopping antibiotics and had 2.7 × 107 and 8.6 × 107 CFU/g recovered from the vegetations. T = 0, CFU of control animals sacrificed 48 h after inoculation.
