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. 2013 Sep;57(9):4489–4495. doi: 10.1128/AAC.00358-13

Table 2.

Frequency of occurrence of BC-3781 MICs for all pathogens (10,035) tested

Organism(s) (no.) Cumulative % of isolates inhibited at BC-3781 MIC (μg/ml) of:
≤0.008 0.015 0.03 0.06 0.12 0.25 0.5 1 2 4 8 16 >16
Staphylococcus aureus (5,527) 0.0 0.1 1.0 43.1 94.6 99.5 99.8 99.8 99.9 99.9 99.9 >99.9 100.0
    MSSA (3,157) 0.0 0.2 1.0 46.9 98.2 99.7 99.8 99.8 99.9 99.9 99.9 99.9 100.0
    MRSA (2,370) 0.0 0.1 0.9 38.1 89.7 99.2 99.8 99.8 100.0 100.0
Coagulase-negative Staphylococcus spp. (878) 0.6 2.7 46.1 85.4 93.7 94.6 96.6 97.8 98.5 99.0 99.3 99.4 100.0
    MSCoNS (241) 1.2 3.7 49.8 92.9 97.9 97.9 97.9 99.6 99.6 100.0
    MRCoNS (637) 0.3 2.4 44.7 82.6 92.2 93.4 96.1 97.2 98.1 98.6 99.1 99.2 100.0
Viridans group streptococci (245) 4.1 15.1 27.3 47.8 70.6 84.1 96.7 98.4 100.0
Beta-hemolytic streptococci (763) 0.5 19.0 93.2 98.4 99.0 99.3 99.3 99.3 99.3 99.6 99.6 100.0
    Group A Streptococcus (267) 0.4 37.8 98.9 100.0
    Group B Streptococcus (334) 0.6 9.6 94.3 98.2 98.5 98.5 98.5 98.5 98.5 99.1 99.1 100.0
Enterococcus faecium (536) 0.0 0.2 2.4 42.9 76.5 81.5 86.0 88.1 89.6 91.8 92.5 94.6 100.0
    Vancomycin susceptible (232) 0.0 0.0 1.3 31.5 62.5 69.0 75.4 76.3 78.0 81.9 83.2 87.9 100.0
    Vancomycin nonsusceptible (304) 0.0 0.3 3.3 51.6 87.2 91.1 94.1 97.0 98.4 99.3 99.7 99.7 100.0
Streptococcus pneumoniae (1,473) 0.2 1.0 4.3 18.0 62.3 95.0 99.8 100.0
    Penicillin susceptible (903) 0.3 1.0 4.0 17.6 61.2 94.0 99.8 100.0
    Penicillin intermediate (258) 0.0 1.2 7.8 18.2 55.0 93.4 99.6 100.0
    Penicillin resistant (312) 0.0 0.6 2.6 18.9 71.2 99.0 100.0
Haemophilus influenzae (360) 0.0 0.3 0.3 0.3 0.3 3.3 38.3 86.1 98.3 99.4 100.0
    β-Lactamase positive (85) 0.0 0.0 0.0 0.0 0.0 4.7 30.6 80.0 97.6 98.8 100.0
    β-Lactamase negative (275) 0.0 0.4 0.4 0.4 0.4 2.9 40.7 88.0 98.5 99.6 100.0
Moraxella catarrhalis (253) 2.8 3.6 4.3 6.7 69.2 98.8 100.0