Fig 1.

Amino acid sequence comparison of the Eat(A) and Eat(A)_v ABC proteins with Lsa-like proteins involved in MLS resistance, Lsa(A), Lsa(B), Lsa(C), and Lsa(E). The two copies of Walker A and B motifs and ABC signatures are boxed. Similarities in amino acid sequences are marked by asterisks (same amino acid), colons (strong similarity), and dots (family similarity). Multiple-sequence alignment was done with ClustalX 1.83 software. The location of the Thr450Ile substitution is indicated by an arrow.