Table 1.
Inhibition of 2696r and HCMV UL97Δ498 replication by ganciclovir and cyclopropavir
| Compound | Comparison of Towne and 2696r |
Comparison of AD169rv and HCMV UL97Δ498 |
||||
|---|---|---|---|---|---|---|
| EC50 (μM)a for: |
Fold resistance of 2696r | EC50 (μM)b for: |
Fold resistance of HCMV UL97Δ498 | |||
| Towne | 2696r | AD169rv | HCMV UL97Δ498 | |||
| GCV | 1.5 ± 0.16 | 41.3 ± 2.8 | 28 | 2.0 ± 0.24 | 28.1 ± 6.6 | 14 |
| CPV | 0.91 ± 0.15 | 22.5 ± 3.5 | 25 | 0.36 ± 0.11 | 25.8 ± 3.1 | 72 |
a
Values are means ± standard deviations from at least two experiments.
b
Values are means ± standard deviations from at least four experiments.