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. 2013 Sep 15;140(18):3731–3742. doi: 10.1242/dev.096560

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Fig. 6. — Early Fgf10 overexpression prevents proximal differentiation whereas Fgf10 overexpression after E12.5 promotes basal cell differentiation. (A-D) Immunostaining for Sox2 on E18.5 control (ctrl) (A) and Rosa26-rtTA;Tet-Fgf10 lungs induced from E11.5 (B), E12.5 (C) and E13.5 (D). (E-H) Immunostaining for Sox9 on E18.5 ctrl (E) and Rosa26-rtTA;Tet-Fgf10 lungs induced from E11.5 (F), E12.5 (G) and E13.5 (H). (I-L) Immunostaining for p63 and K5 on E18.5 ctrl (I) and Rosa26-rtTA;Tet-Fgf10 lungs induced from E11.5 (J), E12.5 (K) and E13.5 (L). (M-P) Immunostaining for Sftpc and Scgb1a1 on E18.5 ctrl (M) and Rosa26-rtTA;Tet-Fgf10 lungs induced from E11.5 (N), E12.5 (O) and E13.5 (P). n≥3. Scale bars: 200 μm (A-H); 100 μm (I-P).