Table 3.

Comparison of sensitivities and specificities of indirect ELISAs using native and recombinant antigens

Calculation	Antigen
	CE	SA	rOmp28	rOmp31
Sensitivity (%)a	68.7	71.7	91.6	62.2
Specificity (%)b	91.9	95.3	97.6	94.7
Correlation (%) with RBPTc	84.8	88.5	92.7	85.7
Correlation (%) with STATc	85.5	89.7	94.2	87.2
Correlation (%) with 2ME testc	87.8	91.9	96.2	90.4
Likelihood ratio for positive resultd	8.5	15.3	38.2	11.7
Likelihood ratio for negative resulte	2.9	3.4	11.6	2.5

^aSensitivity = [true positives/(true positives + false negatives)] × 100.

^bSpecificity = [true negatives/(true negatives + false positives)] × 100.

^cCorrelation = [(number of samples positive by both tests + number of samples negative by both tests)/total number of samples] × 100.

^dLikelihood ratio for positive result = sensitivity/1 − specificity.

^eLikelihood ratio for negative result = specificity/1 − sensitivity.