Table 4.
HLA-DR binding prediction by ProPred analysis for the sequences of complete protein and synthetic peptides (P1 to P6) of RD1 PE35
| Peptide sequence (aa) | No. of alleles predicted to bind/no. of alleles included in ProPred for HLA-DRB allele: |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 1.1 | 1.3 | 1.4 | 1.7 | 1.8 | 1.11 | 1.13 | 1.15 | 5.1 | All alleles | |
| PE35 (1–99) | 2/2 | 6/7 | 9/9 | 0/2 | 3/6 | 9/9 | 10/11 | 2/3 | 2/2 | 43/51 |
| P1 (1–25) | 0/2 | 0/7 | 0/9 | 0/2 | 0/6 | 0/9 | 0/11 | 0/3 | 0/2 | 0/51 |
| P2 (16–40) | 0/2 | 0/7 | 0/9 | 0/2 | 0/6 | 0/9 | 0/11 | 0/3 | 0/2 | 0/51 |
| P3 (31–55) | 1/2 | 0/7 | 0/9 | 0/2 | 0/6 | 0/9 | 1/11 | 0/3 | 0/2 | 2/51 |
| P4 (46–70) | 2/2 | 6/7 | 9/9 | 0/2 | 3/6 | 9/9 | 10/11 | 2/3 | 2/2 | 43/51 |
| P5 (61–85) | 0/2 | 0/7 | 0/9 | 0/2 | 0/6 | 1/9 | 0/11 | 0/3 | 0/2 | 1/51 |
| P6 (76–99) | 0/2 | 0/7 | 0/9 | 0/2 | 0/6 | 0/9 | 0/11 | 0/3 | 0/2 | 0/51 |