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Histopathology. (A) BALB/c mouse lung inoculated with DMEM. At 5 days p.i., the lung was free of inflammatory cell infiltrates with normal pulmonary alveoli. The HPS was 2.63 ± 0.52. (B and C) BALB/c mouse lung inoculated with M2 (B) or WT (C) and at 5 days p.i. showing infiltration of mononuclear cells. The HPSs were 10.75 ± 1.04 (M2) and 16.25 ± 1.0 (WT). P < 0.05 for M2 versus WT (Student's t test). Hematoxylin-eosin stain was used. Magnifications, ×200 (A) and ×100 (B and C).
