Table 1.
Gene | Position | Nucleotide sequence or amino acid |
||
---|---|---|---|---|
NL/1/00 | WT | M2 | ||
F | 3352 | TCT | CCT | CCT |
3565 | AAT | CAG | ||
3567 | AAT | CAG | ||
L | 8335 | TGG | TTG | TTG |
10040 | AAT | AAA | ||
10045 | GCG | GAG | ||
12203 | TGC | TGT | TGT | |
F/M2 | 4690 | Ins C | ||
4693 | Ins T | |||
4695 | Ins A | |||
4696 | Ins A | |||
4697 | Ins A | Ins A | ||
4699 | Ins A | |||
4700 | Ins A | |||
4701 | Ins A | |||
4703 | Ins T | |||
CDS | 101 | S | P | P |
172 | N | Q | ||
172 | N | Q | ||
386 | W | L | L | |
958 | N | K | ||
973 | A | E | ||
1679 | C | C | C |
For the F and L genes and the noncoding region between the F and M2 (F/M2), the nucleotide position is numbered from the 3′ end of the negative-sense RNA (GenBank accession no. AF371337). For CDS, the position is the protein position from the N terminus. Underlining indicates the nucleotide changes resulting in a mutated amino acid. F, fusion protein; L, large polymerase protein; M2, putative protein with a molecular mass of 22 kDa; NL/1/00, wild-type strain NL/1/00; Ins, insertion.