Table 2.
Day p.i. | Inoculum | Mean viral titer (log10 PFU/g ± SD) |
---|---|---|
5 | DMEM | 0 |
5 | M2 | 0 |
5 | WT | 4.94 ± 0.56 |
14 | DMEM | 0 |
14 | M2 | 0 |
14 | WT | 0 |
Eight mice in each group were inoculated with DMEM (negative control) or the WT or M2 virus. The viral titer was measured by florescent plaque assay at 5 and 14 days p.i. If the viral titer was 0, the minimum detectable titer was assigned for the statistical analysis. P < 0.001 for the M2 and DMEM group versus the WT group; P = 1 for the DMEM group versus the M2 group. All P values were determined by one-way ANOVA. The limit of detection was 100 PFU/g.