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Schematic model of the regulation of SM production and development by HstD/AoHst4 through LaeA. An unknown signal induces or suppresses the function of HstD/AoHst4. Suppression of HstD/AoHst4 leads to expression of LaeA. This activation stimulates fungal development and secondary metabolite production. However, there is the possibility of an HstD/AoHst4 competitive mechanism by an unknown factor (described as factor X in this figure).
