Table 3.
Phage tested | Susceptibility of each RopA1 variant or other allele |
|||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
WT | G84A | G84D | G84R | G84V | S87F | S87Y | S89P | ΔN121-D123 | ΔA122-N124 | ΔG203-V204 | 205::GV | ΔN124-D125 | 126::ND | G129D | D134Y | A199V | ΔV204-T205 | lpsB | ropA2 | |
ΦM12 | S | R | R | R | R | R | R | R | R | R | R | R | S | S | S | S | S | S | S | S |
ΦM7 | S | R | R | R | R | R | R | R | R | R | R | R | S | S | S | S | S | S | S | S |
ΦM19 | S | R | R | R | R | R | R | R | R | R | R | R | S | S | S | S | S | S | S | S |
N3 | S | S | S | S | S | R | R | R | R | R | R | R | R | R | R | R | R | S | S | S |
ΦM1 | S | R | R | R | R | R | R | R | R | R | R | R | R | R | R | R | R | R | R | S |
ΦM6 | S | R | R | R | R | R | R | R | R | R | R | R | S | S | R | R | R | R | R | S |
ΦM5 | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | R | R | S |
ΦM9 | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | R | R | S |
ΦM10 | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | R | S |
ΦM14 | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | S | R | S |
RopA1 variants are indicated across the top. The Δ symbol indicates amino acid deletions, and the :: symbol indicates amino acid insertions. Loss-of-function alleles of lpsB and ropA2 are also indicated. S, susceptible; R, resistant.