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HMGCS multiple-sequence alignment. The sequence of HvHMGCS was aligned with previously characterized HMGCSs from E. faecalis (EfMVAS) and Homo sapiens (HsHMGCS). Conserved residues are in black, and similar residues are in gray. Catalytically important residues are indicated by asterisks. Residues flanking catalytically conserved residues used to create maximum-parsimony trees are indicated by plus signs.
