Table 5.
Performance of several previously published schemes for molecular typing of P. jirovecii, evaluated by the Hunter index
| Molecular typing scheme | Discriminatory power according to our data (H-index) | No. of clinical samples used for determination of H-indexa | Reference(s) or source |
|---|---|---|---|
| ITS1, β-TUB, 26S, mt26S, CYB, SOD, DHPS, DHFR | 0.996 | 23 | This study |
| ITS1, mt26S, CYB | 0.996 | 23 | This study |
| SOD, mt26S, CYB | 0.987 | 22 | This study |
| ITS1, 26S, mt26S, β-TUB | 0.987b | 22 | 14, 15, 17, 30–32 |
| ITS1, CYB | 0.983 | 22 | This study |
| mt26S, CYB | 0.957 | 23 | This study |
| ITS1, mt26S | 0.948 | 22 | 24 |
| ITS1 | 0.828 | 28 | 21 |
| mt26S | 0.751 | 29 | 22, 33 |
a
Only samples containing a single P. jirovecii genotype were included in the analysis.
b
The discriminatory power of this method (when used as a PCR-SCCP) was 0.93.