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Genotypic prediction of HIV-1 subtype D tropism using a GenBank data set of known phenotype
| Genotyping tool and TTT phenotype | TTT phenotype |
Performance of the genotyping tool |
|||
|---|---|---|---|---|---|
| R5 | X4 | % Sensitivity | % Specificity | % Concordance (kappa value) | |
| G2P 10 | |||||
| R5 | 33 | 3 | 91 | 56 | 68 (0.41) |
| X4 | 26 | 31 | |||
| G2P 5 | |||||
| R5 | 45 | 5 | 85 | 76 | 79 (0.58) |
| X4 | 14 | 29 | |||
| G2P 2.5 | |||||
| R5 | 52 | 8 | 76 | 88 | 84 (0.65) |
| X4 | 7 | 26 | |||
| Combined D rule | |||||
| R5 | 58 | 13 | 62 | 98 | 85 (0.64) |
| X4 | 1 | 21 | |||
