Table 1.
Performances of ms-AFST and the CLSI method for 62 clinical C. albicans isolates according to the presence or absence of FKS1 hot spot mutationsa
| Method | Total no. of isolates (fks1/WT) | No. (%) of misclassified isolates |
|||
|---|---|---|---|---|---|
| CA | VMEs | MEs | mEs | ||
| ms-AFST | 62 (11/51) | 61/62 (98.4) | 1/62 (1.6) | 0/62 | NAb |
| CLSI | 62 (11/51) | 61/62 (98.4) | 0/62 | 0/62 | 1/62 (1.6) |
a
Very major errors (VMEs) were identified when fks1 mutant isolates were classified as absent by ms-AFST or the CLSI method. Major errors (MEs) were identified when wild-type (WT) isolates were classified as present by ms-AFST or the CLSI method. Minor errors (mEs) were identified when fks1 mutant and WT isolates were classified as intermediate by the CLSI method only. CA, categorical agreement.
b
NA, not applicable.