Table 2.
Selected characteristics of children with invasive staphylococcal infections at Alfred I. DuPont Hospital for Children, 1 April 2000 to 32 March 2008
| Characteristica | No. (%) of MSSA isolates with vancomycin MICs (μg/ml) of:b |
Pd | No. (%) of MRSA isolates with vancomycin MICs (μg/ml) of:c |
Pd | ||||
|---|---|---|---|---|---|---|---|---|
| ≤1 (n = 226) | 1.5 (n = 118) | 2 (n = 19) | ≤1 (n = 40) | 1.5 (n = 22) | 2 (n = 11) | |||
| Age (yr) | ||||||||
| ≤2 | 71 (32) | 39 (33) | 7 (37) | 9 (22.5) | 6 (27) | 4 (36) | ||
| >2 to ≤12 | 100 (44) | 52 (44) | 9 (47) | 22 (55) | 6 (27) | 5 (46) | ||
| >12 | 55 (24) | 27 (23) | 3 (16) | 0.9 | 9 (22.5) | 10 (46) | 2 (18) | 0.2 |
| Gender | ||||||||
| Male | 133 (59) | 68 (58) | 11 (58) | 26 (65) | 18 (82) | 6 (54.5) | ||
| Female | 93 (41) | 50 (42) | 8 (42) | 0.9 | 14 (35) | 4 (18) | 5 (45.5) | 0.2 |
| Infection site | ||||||||
| Blood | 128 (57) | 76 (64) | 9 (47) | 23 (57.5) | 13 (59) | 7 (64) | ||
| MS | 87 (38.5) | 36 (31) | 7 (37) | 14 (35) | 7 (32) | 3 (27) | ||
| CSF | 8 (3.5) | 5 (4) | 2 (11) | 3 (7.5) | 2 (9) | 1 (9) | ||
| Pleural | 3 (1) | 1 (1) | 1 (5) | 0.3 | 0 | 0 | 0 | 0.9 |
| Previous vancomycin exposure | 60 (27) | 34 (29) | 5 (26) | 0.9 | 13 (45) | 5 (23) | 4 (36) | 0.6 |
a
MS, musculoskeletal; CSF, cerebrospinal fluid.
b
Total n = 363.
c
Total n = 73.
d
Pearson's chi-square.