Table 6.
Predictive value of six bacterial taxa at sites 6 months prior to bone loss compared to sites that remained healthy
| Bacterial taxa and HOMIM probe no. | Probe presence | No. of sites breakdown+a | No. of sites breakdown−b | Performance characteristic (%) |
|||
|---|---|---|---|---|---|---|---|
| Sensitivity | Specificity | Positive predictive value | Negative predictive value | ||||
| Aggregatibacter actinomycetemcomitans | + | 18 | 32 | ||||
| HOT-531 probe-AA84 | − | 0 | 52 | 100 | 62 | 36 | 100 |
| Porphyromonas gingivalis | + | 9 | 17 | ||||
| HOT-619 probe-AA93 | − | 9 | 67 | 50 | 80 | 35 | 88 |
| Fusobacterium cluster | + | 4 | 39 | ||||
| HOT-200, -201, -202, -203, -205, -370, -420, -689 probe-AD99 | − | 14 | 45 | 22 | 54 | 9 | 76 |
| Filifactor alocis | + | 18 | 33 | ||||
| HOT-539 probe-AA69 | − | 0 | 51 | 100 | 61 | 35 | 100 |
| Streptococcus parasanguinis cluster | + | 14 | 13 | ||||
| HOT-057, -411, -721 probe-V77 | − | 4 | 71 | 78 | 85 | 52 | 95 |
| Veillonella dispar-Veillonella parvula-Veillonella rogosae | + | 16 | 18 | ||||
| HOT-158-160-161 probe-D96 | − | 2 | 66 | 89 | 79 | 47 | 97 |
a
Eighteen sites in 16 subjects that showed bone loss used to calculate sensitivity, specificity, and predictive values.
b
Eighty-four healthy sites that remained healthy and thus did not show bone loss in these same 16 subjects used to calculate sensitivity, specificity, and predictive values.