The enhanced system induction potential of shp3 compared to shp2 is not a consequence of differential promoter strengths. (A) Luciferase expression from a Pshp2 reporter integrated into WT (BNL148), Δrgg3 (BNL149), Δrgg3 shp3GGG (BNL203), Δrgg3 shp2GGG (BNL176), Δrgg3 Δshp3→shp2 shp2GGG (BNL220), and Δrgg3 Δshp2→shp3 shp3GGG (BNL216) strains. (B) Luciferase expression from Pshp2 reporter integrated into WT (BNL148), Δrgg3 (BNL149), Δrgg3 Δshp3→shp2 (BNL202), Δrgg3 Δshp2→shp3 (BNL192), and Δrgg3 Δshp3→shp2 Δshp2→shp3 (BNL222) strains. Expression trends are representative of at least three independent experiments.