Table 4.
Blood and CSF lactate and pyruvate concentrations in patients with PDC deficiency.
| Blood Lactate (mmol/L) | Blood Pyruvate (mmol/L) | Blood L:P Ratio | CSF Lactate (mmol/L) | CSF Pyruvate (mmol/L) | |
|---|---|---|---|---|---|
| Total | 7.8 ± 5.6 (216) | 0.76 ± 2.3 (118) | 19.6 ± 22 (45) | 6.1 ± 3.04 (123) | 0.47 ± 0.27 (43) |
| E1 | 9.9 ± 8.2 (16) | 0.67 ± 0.99 (15) | 18.6 ± 7.2 (5) | 5.90 ± 4.5 (9) | 0.57 ± 0.4 (4) |
| E1a | 7.02 ± 5.8 (115) | 0.56 ± 0.83 (66) | 20.1 ± 25.6 (32) | 6.07 ± 3 (74) | 0.48 ± 0.27 (26) |
| E1b | 11.8 ± 6.6 (8) | 20.2 ± 0.28 (2) | |||
| E2 | 2.58 ± 2.1 (3) | 0.137 (1) | 1.4 ± 0.39 (2) | ||
| E3 | 11.3 ± 4.6 (15) | 4.37 ± 8.6 (7) | 3.01 ± 1.47 (4) | ||
| E3BP | 10.3 ± 6.9 (21) | 0.56 ± 0.43 (10) | 13.4 ± 4.7 (5) | 6.03 ± 2.3 (6) | 0.53 ± 0.06 (2) |
| Unclassified | 6.0 ± 2.6 (38) | 0.37 ± 0.19 (19) | 17.6 (1) | 6.9 ± 2.8 (28) | 0.40 ± 0.26 (11) |