Figure 7.
Functionally anti-correlated task-positive (activation, red) and negative (deactivation, blue) networks involved in acupuncture action shown on a brain sketch, with an overlapping of medial and lateral regions. Regions of deactivation in the limbic–paralimbic–neocortical network aggregate in the medial frontal, parietal and temporal lobes. The basal ganglia, the cerebellar vermis, tonsil and brainstem also show regional deactivation. The cingulate and thalamus have regions in both networks, while the sensorimotor areas, insula, middle cingulate and the dorsal division of posterior cingulate Brodmann area 23 are in the task-positive network. The figure is adapted from Hui et al. (2009). Abbreviations: ant middle C, anterior middle cingulate; BA Brodmann area; BA23d, Brodmann area 23 dorsal; BA23v, Brodmann area 23 ventral; BG, basal ganglia; FP, frontal pole; Hyp, hypothalamus; M1/S1, primary motor/primary sensory cortex; OFC, orbitofrontal cortex; PAG, periaqueductal gray; PB, parabrachial nucleus; preg C, pregenual cingulate; SII, secondary somatosensory cortex; SMA, supplementary motor area; SG25, subgenual area 25; Subg C, subgenual cingulate, TA, tract A; TB, tract B.