Figure 6.
CDDO-Me downregulates FASN and S14 expression in LiSa-2 cells. Quantitative real-time PCR (45 cycles) results for fatty acid synthase (FASN) and S14 mRNAs in LiSa-2 (A and C) and fibroblast (B and D) cells after 12-day exposure to 100 nM CDDO-Me or vehicle alone. Data (mean ± SEM, n=6/group) are normalized to the cyclophilin signal and are expressed as a percent of control. *p<0.01 compared to vehicle treatment.