Table 1.
T-cell subset distribution in IELs and TDLs
| Frequency | |||||
| CD3+ | γδ | Vγ7 | uncTCRαβc | CD8αβ | CD4 |
| % | % | % | % | % | |
| IELsa | 46.5 ± 11.5 (49) | 30.6, 65.9 ± 9.6 (8)d | 20.08 ± 7.4 (47) | 21.2 ± 9.7 (47) | 10.3 ± 6 (47) |
| TDLsa | 1.44 ± 0.5 (52) | 0.08, 5.6 ± 2.2 (14)d | 0.59 ± 0.3 (39) | 37.7 ± 6.8 (40) | 58.9 ± 7.1 (40) |
| RTEsb | 2.65 ± 1 (8) | 0.24, 11.5 ± 1.4 (3)d | 0.71 ± 0.4 (9) | 24 ± 3.8 (8) | 72.1 ± 4.4 (8) |
Values in parentheses show the number of mice individually analyzed.
a
Percent CD3+ cells: TDLs, 76 ±10; IELs, 84 ± 6.9.
b
6–12 wk-old RAG2p-GFP mice. Percent GFP+ in CD3+ TDLs: 23 ± 2.6. The frequency of unconventional T cells in RTEs was independent of the age of the mice.
c
NK-T cells were excluded with an anti-NK1.1 mAb. Similar results were obtained in CD1−/− mice.
d
Percent Vγ7+ in γδ T-cells.