Table 2.
Response to liposomal amphotericin B in 91 patients
| Single dose | Five dose | |
|---|---|---|
| Regimen | 5 mg/kg×1 | 1 mg/kg/day×5 |
| No of participants | 46 | 45 |
| No completing treatment | 46 | 45 |
| No in whom treatment failed | 1 | 1 |
| No with apparent cure* | 45 | 44 |
| No with relapses | 3 | 2 |
| No with definitive cure† | 42 | 42 |
| Rate of cure (%, 95% CI)‡ | 91 (79 to 98) | 93 (82 to 99) |
Evaluated 14 days after last treatment (day 15 in single dose group and day 19 in five dose group).
Evaluated 6 months after treatment in all patients with apparent cure.
Cure rates were not significantly different between the groups (95% confidence interval −13.6% to 20.9%, P=1.0, Fisher exact test).