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. Author manuscript; available in PMC: 2013 Aug 27.
Published in final edited form as: JAMA. 2012 Mar 28;307(12):1284–1291. doi: 10.1001/jama.2012.340

APPENDIX TABLE 2.

Sensitivity analysis of association between OOP asthma medication costs and asthma medication utilization and asthma -related hospitalizations, children ages 5–18

Annual OOP cost for asthma medications
25th percentile ($100) Mean (95% CI) 75th percentile ($190) Mean (95% CI) p-value
Follow-up period of 90 days (rather than 365 days)
% of days covered by an asthma medication prescription 63.2 (62.1–64.2) 62.0 (61.1–62.8) 0.02
90-day rate of asthma-related hospitalization per 100 children 0.5 (0.3–0.7) 0.8 (0.5–1.1) 0.04
Requirement of 12 months without control therapy (rather than 6 months) to be included in sample
% of days covered by an asthma medication prescription 42.3 (41.2–43.5) 40.8 (39.8–41.8) 0.03
Annual rate of asthma-related hospitalizations per 100 children 1.4 (1.1–1.8) 2.2 (1.6–2.7) 0.007
Sample restricted to children initiating therapy during pollen season (April to September)
% of days covered by an asthma medication prescription 44.4 (43.2–45.6) 43.0 (42.0–44.0) 0.03

Notes: Annual OOP cost and expenditures on hospitalization are in 2010 dollars. Requirement of 12 months without control therapy (rather than 6 months) reduces sample to 4,502 children. Restricting sample to children initiating therapy during pollen season reduces sample to 2,715 children.