Table 2. Predictors of positive TST and T-SPOT.TB result in multivariate logistic regression analysis.
| Positive TST | Positive T-SPOT.TB | Dual Positive* | |||||||
| Variables | aOR | CI | p value | aOR | CI | p value | aOR | CI | p value |
| Age | 0.99 | 0.97–1.01 | 0.444 | 1.02 | 1.00–1.05 | 0.034 | 1.01 | 0.99–1.04 | 0.345 |
| Male gender | 1.46 | 0.87–2.47 | 0.157 | 2.34 | 1.17–4.68 | 0.016 | 3.33 | 1.27–8.76 | 0.015 |
| HIV transmission risk category | |||||||||
| MSM | 1 | 1 | 1 | ||||||
| Heterosexual | 1.74 | 0.97–3.12 | 0.065 | 1.63 | 0.84–3.17 | 0.147 | 1.91 | 0.80–4.55 | 0.144 |
| IDU | 1.08 | 0.53–2.18 | 0.830 | 1.97 | 0.88–4.42 | 0.101 | 1.63 | 0.54–4.87 | 0.385 |
| HIV-related factors | |||||||||
| AIDS status | 1.09 | 0.65–1.82 | 0.756 | 1.14 | 0.63–2.06 | 0.675 | 1.69 | 0.78–3.66 | 0.185 |
| CD4+ lymphocyte (per 100 cells/mm3) | 1.25 | 1.16–1.36 | 0.000 | 1.16 | 1.06–1.26 | 0.001 | 1.31 | 1.17–1.48 | 0.000 |
| HIV RNA(log10) | 0.78 | 0.63–0.97 | 0.023 | 0.96 | 0.75–1.22 | 0.753 | 1.04 | 0.75–1.44 | 0.800 |
| On ART at enrollment | 0.78 | 0.39–1.57 | 0.493 | 0.96 | 0.43–2.13 | 0.921 | 1.15 | 0.39–3.41 | 0.799 |
| BCG vaccination | 1.21 | 0.57–2.57 | 0.617 | 0.51 | 0.25–1.02 | 0.058 | 0.58 | 0.23–1.45 | 0.246 |
| Self-reported contact with active TB case | 2.10 | 1.10–4.01 | 0.024 | 2.77 | 1.42–5.42 | 0.003 | 4.11 | 1.90–8.89 | 0.000 |
| Prison stay# | 2.67 | 1.34–5.31 | 0.005 | 1.31 | 0.59–2.88 | 0.510 | 2.41 | 0.81–7.11 | 0.112 |
Definition of abbreviations: aOR = adjusted Odds ratio; CI = 95% confidence interval; MSM = man who had sex with man; IDU = injecting drug use; ART = highly active antiretroviral therapy; BCG = Bacille Calmette-Guérin; TST = tuberculin skin test.
*use participants with dual negative results as the reference group.
#
duration over 6 months.
All variables were included in multiple logistic regression analysis for adjustment.