Table 3. Agreement between T-SPOT.TB assay and Tuberculin Skin Tests, stratified by age and CD4+ lymphocyte counts groups and BCG vaccination status.
| TST* | T-SPOT.TB | TST and T-SPOT.TB | Agree-ment | Kappa (95% CI) | ||
| (% of the category) | ||||||
| All patients | (n = 909) | 25.0% | 14.7% | 8.9% | 78.1% | 0.32(0.24–0.41) |
| Age | ||||||
| <30 years | (n = 221) | 21.7% | 9.5% | 5.4% | 79.6% | 0.25(0.05–0.44) |
| 30–39 years | (n = 407) | 28.3% | 13.5% | 8.8% | 75.9% | 0.30(0.17–0.41) |
| ≧40 years | (n = 281) | 22.8% | 20.6% | 11.7% | 80.1% | 0.41(0.28–0.55) |
| CD4+ lymphocyte count | ||||||
| <200 | (n = 56) | 8.9% | 10.7% | 7.1% | 94.6% | 0.70(0.37–1.00) |
| 200–349 | (n = 225) | 14.7% | 8.0% | 4.0% | 85.3% | 0.28(0.05–0.51) |
| 350–499 | (n = 265) | 23.8% | 17.4% | 9.1% | 77.0% | 0.30(0.150.45) |
| ≧500 | (n = 363) | 34.7% | 17.6% | 12.1% | 71.9% | 0.30(0.18–0.42) |
| BCG scar | ||||||
| 0 | (n = 51) | 21.6% | 29.4% | 15.7% | 80.4% | 0.49(0.20–0.77) |
| 1 | (n = 464) | 24.6% | 15.1% | 9.5% | 79.3% | 0.36(0.24–0.47) |
| 2 | (n = 358) | 27.4% | 13.7% | 8.1% | 75.1% | 0.26(0.13–0.39) |
Definition of abbreviations: BCG = Bacille Calmette-Guérin; TST = tuberculin skin test.
*A TST reaction ≧5 mm was considered as positive.