Table 2. Kruskal-Wallis H tests of associations between glucose intolerance status and microbiota composition (OTUs level).

OTU	P	Occurrence rate			Taxon	Identity
		NGT	Pre-DM	T2DM
NGT enrichment:
6275	0.0081626	0.18	0.02	0.08	Bacteroides	1
2101	0.0064251	0.77	0.56	0.38	Blautia	0.98
2340	0.0087904	0.07	0.25	0.00	Clostridiales	1
3265	0.0054547	0.27	0.52	0.08	Haemophilus	0.86
4375	0.001644	0.32	0.59	0.23	Lachnospiraceae	0.99
1632	0.009626	0.11	0.30	0.00	Megamonas	1
3209a	0.0024805	0.16	0.39	0.00	Megamonas	1
1900	0.003299	0.50	0.22	0.46	Roseburia	1
T2DM enrichment:
7678	0.0037128	0.05	0.31	0.23	Bacteroides	1
770	0.0057936	0.02	0.23	0.08	Bacteroides	1
6679	0.0047138	0.84	0.63	1.00	Blautia	1
286	0.0020471	0.14	0.05	0.38	Clostridiales	1
5579	0.0071113	0.32	0.13	0.46	Eubacterium	0.96
396	0.0010595	0.11	0.42	0.15	Lachnospiraceae	0.81
2508	0.0009765	0.36	0.70	0.54	Lachnospiraceae	0.84
3325	0.0067516	0.30	0.56	0.62	Lachnospiraceae	0.87
6803	0.0017342	0.55	0.83	0.69	Lachnospiraceae	0.87
6718b	0.0031246	0.39	0.56	0.85	Lachnospiraceae	0.95
4235	0.0098852	0.20	0.50	0.38	Lachnospiraceae	0.96
3249	0.00129	0.07	0.06	0.38	Lachnospiraceae	1
6565	0.0062553	0.07	0.09	0.38	Peptostreptococcus	1
7853	0.0005223	0.07	0.05	0.38	Ruminococcaceae	0.97
469	0.0022403	0.14	0.13	0.54	Ruminococcus	0.97
4393	0.004243	0.18	0.14	0.54	Ruminococcus	1
4508b	0.0028564	0.39	0.48	0.85	Ruminococcus	1
2980	0.0039087	0.05	0.11	0.38	Sporobacter	0.92
4416	0.0045742	0.50	0.39	0.85	Subdoligranulum	0.97
7046	0.0024899	0.02	0.06	0.31	Abiotrophia	0.97

^aThe relative abundance of OTUs enriched in the NGT group decreased to 0 with the development of T2DM.

^bThe relative abundance of OTUs increased with the development of T2DM.

NGT = normal glucose tolerance; OTU = operational taxonomic unit; Pre-DM = prediabetes; T2DM = type 2 diabetes mellitus.