Figure 4. Lungs of bleomycin-treated Cav-2^−/− mice exhibit an increased incidence of apoptotic cells as compared with WT and Cav-1^−/− mice. Whole sections of paraffin-embedded left lungs of wild-type, Cav-1^−/− and Cav-2^−/− mice treated with saline or bleomycin were used for detection of apoptosis by the TUNEL technique. Data were expressed as a percentage of the WT+Bleo group (* p < 0.05, ** p < 0.01, *** p < 0.001, n = 4 to 11 for each group)