Table 4.

Obesity polymorphisms associated with adiposity after δ¹⁵N adjustment

Gene	SNP	BMI	PBF	HC	ThC	WC
NEGR1	rs2815752	0.222	0.056	0.109	0.055	0.081
		(β = −0.3, SE = 0.2)	(β = −0.4, SE = 0.2)	(β = −0.4, SE = 0.2)	(β = −0.6, SE = 0.3)	(β = −0.5, SE = 0.3)
TMEM18	rs7561317	0.048	0.073	0.103	0.202	0.034
		(β = 0.5, SE = 0.2)	(β = 0.4, SE = 0.2)	(β = 0.4, SE = 0.2)	(β = 0.4, SE = 0.3)	(β = 0.6, SE = 0.3)
ETV5	rs7647305	0.006	0.006	0.002	0.003	0.009
		(β = −1.5, SE = 0.6)	(β = −1.4, SE = 0.5)	(β = −1.8, SE = 0.6)	(β = −2.0, SE = 0.7)	(β = −1.9, SE = 0.7)
GNPDA2	rs10938397	0.821	0.761	0.315	0.267	0.867
		(β = 0.1, SE = 0.2)	(β = 0.1, SE = 0.2)	(β = 0.2, SE = 0.2)	(β = 0.3, SE = 0.3)	(β = 0.1, SE = 0.3)
BDNF	rs6265	0.531	0.646	0.943	0.859	0.396
		(β = 0.4, SE = 0.6)	(β = 0.2, SE = 0.5)	(β = 0.0, SE = 0.6)	(β = 0.1, SE = 0.7)	(β = 0.6, SE = 0.7)
MTCH2	rs10838738	0.682	0.550	0.556	0.440	0.797
		(β = 0.1 SE = 0.2)	(β = 0.1, SE = 0.2)	(β = 0.1, SE = 0.2)	(β = 0.2, SE = 0.2)	(β = 0.1, SE = 0.2)
SH2B1	rs7498665	0.111	0.136	0.239	0.092	0.179
		(β = 0.3, SE = 0.2)	(β = 0.2, SE = 0.2)	(β = 0.2, SE = 0.2)	(β = 0.4, SE = 0.2)	(β = 0.3, SE = 0.2)
FTO	rs9939609	0.010	0.004	0.008	0.010	0.020
		(β = 0.6, SE = 0.2)	(β = 0.6, SE = 0.2)	(β = 0.6, SE = 0.2)	(β = 0.7, SE = 0.3)	(β = 0.7, SE = 0.3)
MC4R	rs17782313	0.377	0.726	0.243	0.094	0.328
		(β = 0.3, SE = 0.3)	(β = 0.1, SE = 0.3)	(β = 0.4, SE = 0.3)	(β = 0.6, SE = 0.4)	(β = 0.4, SE = 0.4)
KCTD15	rs29941	0.301	0.192	0.319	0.177	0.405
		(β = 0.2, SE = 0.2)	(β = 0.2, SE = 0.2)	(β = 0.2, SE = 0.2)	(β = 0.3, SE = 0.2)	(β = 0.2, SE = 0.3)

p values for association of obesity SNPs adjusted for age, sex, community group, and n-3 PUFA intake. Estimates of effect size (β) are reported for additive model and BMI-increasing alleles using transformed phenotypes. Results significant at p ≤ 0.005 are highlighted in bold. Body mass index (BMI), percent body fat (PBF), hip circumference (HC), thigh circumference (ThC), and waist circumference (WC)