Table I.
Effect of GA and Its HSPC Complex on SGOT, SGPT, ALP, Total Bilirubin, and Total Protein Levels in CCl4-Induced Toxicity in Rats
| Parameters | Control | CCl4-control (CCl4 1 mL/kg) | GA50 (GA 50 mg/kg) | GA-HSPC50 (GA-HSPC complex ≈ 50 mg/kg GA) | GA+HSPC50 (physical mixture of GA and HSPC ≈ 50 mg/kg GA) | HSPC250 (HSPC 250 mg/kg) |
|---|---|---|---|---|---|---|
| SGOT (IU/L) | 76.43 ± 1.2**, ## | 136.40 ± 7.8## | 108.35 ± 3.5** | 88.31 ± 1.5**, # | 111.96 ± 2.8* | 132.64 ± 6.7## |
| SGPT (IU/L) | 53.22 ± 2.84**, ## | 98.21 ± 1.29## | 79.25 ± 3.76** | 63.37 ± 3.34**, # | 81.59 ± 2.98** | 95.21 ± 1.29## |
| ALP (units/L) | 124.03 ± 4.81**, ## | 210.7 ± 7.37## | 164.33 ± 3.06** | 136.23 ± 3.56**,## | 159.33 ± 4.56** | 205.7 ± 6.47## |
| Total bilirubin (mg/dL) | 0.53 ± 0.02**,## | 0.94 ± 0.03## | 0.70 ± 0.01** | 0.59 ± 0.01**,## | 0.65 ± 0.01** | 0.87 ± 0.03## |
Values are mean ± SEM of six animals
*P <0.05, **P < 0.01 significant with respect to CCl4-treated group; # P < 0.05, ## P < 0.01 significant with respect to GA50 group